Sclerosing adenosis (SA) is a benign proliferative condition of the terminal duct lobular units characterised by an increased number of acini and their glands. English Translation, Synonyms, Definitions and Usage Examples of Spanish Word ‘adenosis esclerosante mamaria’. el diagnóstico diferencial de lesiones benignas que simulan carcinoma, tales como hiperplasia cribiforme, adenosis esclerosante e hiperplasia adenomatosa .

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About Blog Go ad-free. The patient was a smoker. Any hyperplastic process see subtypes below primarily involving glands i. In most cases, sclerosing adenosis is detected during routine mammograms or following breast surgery. Ultrasound-guided fine needle aspiration reported a well-differentiated acinar cell carcinoma low grade.

Adenosis of breast – general. The authors declare that no experiments were performed on humans or animals for this study. Accessed December 31st, Diagn Cytopathol, 38pp.

Se continuar a navegar, consideramos que aceita o seu uso. There are few cases of SPA that have become multinodular.

Most cases appear in the major salivary glands, especially in the parotid gland.

Adenosis of the Breast

It mainly affects the major salivary glands, especially the parotid gland, although it may exceptionally affect the minor salivary glands. The provisional probable diagnosis was a parotid tumor with a clinical and radiological benign behavior, likely a pleomorphic adenoma. You can also scroll through stacks with your mouse wheel or the keyboard arrow keys.


SNIP measures contextual citation impact by wighting citations based on the total number of citations in a subject field. There have been no reports of distant metastases or mortality in this condition.

Articles Cases Courses Quiz. A superficial parotidectomy was done and the microscopic study informed SPA. This item has received. Sclerosis polycyst adenosis of parotid gland: Its aetiology is unknown, although it is clonal and, therefore, neoplastic nature has been reported. With LCIS and microinvasion arrows.

Specific immunohistochemistry antibodies as anti-smooth muscle actin, can confirm the integrity of the myoepithelial cells layer in benign tumors, which is lost in carcinomatous lesions.

Epithelial and myoepithelial cells. A physical examination was done. Home About Us Advertise Amazon.

Pathology Outlines – Sclerosing adenosis

Proliferation of acini and ducts, some of eaclerosante dilated, in a sclerotic stroma with a slight, chronic, inflammatory infiltrate. Circumscribed, partially encapsulated lesion consisting of a proliferation of ducts and acini, esclefosante a lobar pattern and without atypia.

Click here for information on linking to our website or using our content or images. We report a case of sclerosing polycystic adenosis within the submandibular gland in a year-old woman. Sclerosing polycystic adenosis of the minor salivary gland: There have been about 51 cases of sclerosing polycyst adenosis SPA in the salivary glands published. The most common site of presentation of a salivary neoplasm is the parotid gland. Loading Stack – 0 images remaining. Although not considered a pre-malignant lesion, sclerosing adenosis is considered an independent risk factor for development of subsequent breast cancer 3,5.


These tumors are diagnosed at a mean age of 40 years and the mean tumor size is in the range of 0. Multinodular, cuts with increased resistance Gritty but no chalky yellow white foci or streaks.

Figure 2 – The microscopic study reveal a parotid gland tissue with periductal inflammation and fibrosis with intraluminal cellular debris and polymorphic nuclear cells.

The treatment in most cases consists of excision of the tumor with a superficial parotidectomy with adequate surgical margins and facial nerve sparing, which has demonstrated a prolonged survival. Therefore a preauricular parotidectomy was done by cervical incision, removing the supra-facial portion adenosix the right parotid gland. Fibroscopy was normal, whilst bimanual and cervical palpation noticed an enlarged, left submandibular gland, with a posterior adenopathy to a mobile and rolling gland of about 2 cm in diameter.